ĭiclofenac is an NSAID belonging to the family of phenylacetic acids and acts to decrease inflammation as other class drugs do. Studies have also elucidated the benefits of using diclofenac post-operatively to reduce the need for rescue analgesia in patients after surgery. Otherwise, diclofenac is only available via prescription. Diclofenac 1% gel was approved for over-the-counter distribution in February 2020 for the management of arthritic pain. ĭiclofenac has been used off-label to treat biliary colic, corneal abrasion, fever, gout, migraine, myalgia, and post-episiotomy pain. Diclofenac was synthesized in 1973 and is the most widely prescribed NSAID worldwide. It is a non-steroidal anti-inflammatory drug (NSAID) and, although it can help to manage the symptoms of pain during inflammatory processes, it cannot reverse or prevent chronic joint damage seen with osteoarthritis and rheumatoid arthritis. Diclofenac is also FDA approved for ophthalmic administration for the extraction of cataracts, pain in the eye, and photophobia. Topically, it can treat actinic keratosis. These include osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Diclofenac is an FDA-approved drug used in the treatment and management of acute and chronic pain associated with inflammatory conditions, especially those involving the musculoskeletal system.
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